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 Formulary Chapter 14: Immunological products and vaccines - Full Chapter
14.01  Active immunity
14.01  Immunisation schedule
 note  DoH Routine Immunisation Schedule - 2015
14.04  Vaccines and antisera
Japanese Encephalitis Vaccine (Ixiaro)
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Formulary Restricted Item NMGH Travel Clinic only 
   
14.04  Anthrax vaccine
 note  In the event of possible contact with B. anthracis, post-exposure immunisation may be indicated. Advice on the use of anthrax vaccine must be obtained from Public Health England Colindale (tel: 020 8200 4400)
14.04  BCG vaccines to top
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Tuberculosis
BCG vaccine diagnostic agent (Tuberculin PPD)
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Formulary  
Link  PAT Policy: Tuberculosis
   
BCG vaccine Intradermal
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Formulary  
Link  PAT Policy: Tuberculosis
   
14.04  Cholera vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Cholera
Cholera vaccine (Dukoral)
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Formulary Restricted Item NMGH Travel Clinic only 
   
14.04  Diphtheria vaccines
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Diphtheria
Diphtheria with Hib, pertussis, poliomyelitis and tetanus (Infanrix-IPV + Hib)
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Formulary  
   
Diphtheria with Hib, pertussis, poliomyelitis and tetanus  (Pediacel)
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Diphtheria with pertussis, poliomyelitis and tetanus (Repevax)
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Diphtheria with poliomyelitis and tetanus (Revaxis)
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Diphtheria antitoxin
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Restricted Drug Restricted
Red
Microbiology / ID recommendation only 
   
14.04  Haemophilus influenzae type B vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Hib
Haemophilus influenzae type B Combined Vaccine (Menitorix)
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Formulary  
Link  PAT Vaccine schedule for patients with absent or dysfunctional spleen (see p.56 of policy)
   
14.04  Hepatitis A vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Hepatitis A
Hepatitis A vaccine Single Component (Havrix)
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Formulary  
   
Hepatitis A vaccine with Hepatitis B vaccine  (Twinrix)
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Hepatitis A vaccine with typhoid vaccine (Hepatyrix®)
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Hepatitis A vaccine with typhoid vaccine (VIATIM®)
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Formulary  
   
14.04  Hepatitis B vaccine to top
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Hepatitis B
Hepatitis B vaccine Single Component (HBvaxPRO)
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Formulary  
   
Hepatitis B vaccine Single Component (Engerix B)
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Hepatitis B vaccine Single Component (Fendrix)
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Approved by Medical D&T on 26/3/15 for use after failure of previous vaccination course, as per BHIVA guidelines. 
Link  BHIVA Guidelines on the use of vaccines in HIV positive adults
   
14.04  Human papilloma virus vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): HPV
Human papilloma virus vaccine (Gardasil)
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Formulary  
   
14.04  Influenza vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Influenza
Inactivated Influenza Vaccine (Split Virion)
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Formulary  
   
14.04  Measles, Mumps and Rubella (MMR) vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Measles 
help DoH Immunisation Against Infectious Diseases (Green Book): Mumps 
help DoH Immunisation Against Infectious Diseases (Green Book): Rubella
Measles, Mumps and Rubella Vaccine, Live (MMR)
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Formulary  
   
14.04  Meningococcal vaccines
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Meningococcal
Meningococcal group B Vaccine (Bexsero)
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Meningococcal group C conjugate vaccine (NeisVac-C)
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Formulary  
   
Meningococcal polysaccharide A, C, W135 and Y vaccine (Nimenrix or Menveo)
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Formulary  
Link  PAT Vaccine schedule for patients with absent or dysfunctional spleen (see p.56 of policy)
   
14.04  Pneumococcal vaccines to top
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Pneumococcal
Pneumococcal vaccine
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Formulary Previously known as Pneumovax II 
Link  PAT Vaccine schedule for patients with absent or dysfunctional spleen (see p.56 of policy)
   
Pneumococcal vaccine (Prevenar 13)
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Formulary  
   
14.04  Rabies vaccine
 note 

help DoH Immunisation Against Infectious Diseases (Green Book): Rabies

Rabies vaccine
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Formulary Pre-exposure vaccination: NMGH Travel Clinic only 
   
14.04  Rotavirus vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Rotavirus
Rotavirus vaccine (Rotarix)
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Formulary  
   
14.04  Tetanus vaccines
 note  See Diphtheria-containing vaccines
help DOH Immunisation Against Infectious Diseases (Green Book): Tetanus
14.04  Tick-borne encephalitis vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Tick-borne encephalitis
Tick-borne encephalitis vaccine
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Formulary Restricted Item NMGH Travel Clinic only 
   
14.04  Typhoid vaccines to top
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Typhoid
Polysaccharide vaccine for injection (Typhim Vi®)
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Formulary  
   
14.04  Varicella-zoster vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Varicella
Varicella-zoster vaccine (Varivax®)
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Formulary  
   
14.04  Yellow fever vaccine
 note  help DoH Immunisation Against Infectious Diseases (Green Book): Yellow Fever
Yellow fever vaccine (Live)
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Formulary NMGH Travel Clinic only 
   
14.05  Immunoglobulins
14.05.01  Normal immunoglobulin
 note  DoH Clinical Guidelines for Immunoglobulin Use
The National Immunoglobulin Database
PAT Intravenous Human Immunoglobulin Policy
Normal immunoglobulin for Intravenous use (Octagam)
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First Choice
Red
 
Normal immunoglobulin for Intravenous use (Vigam)
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Formulary
Red
Restricted Item Established patients only 
   
Normal immunoglobulin for subcutaneous or intramuscular use (Subgam)
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Restricted Drug Restricted
Red

Restricted Item Only for prophylaxis of tetanus-prone wounds when IM tetanus immunoglobulin unavailable


See Public Health England (PHE) Guidance for full details

 
Link  PHE: Recommendations on the treatment and prophylaxis of tetanus
   
14.05.02  Disease-specific immunoglobulins to top
 note  Public Health England Guidance: Immunoglobulins - when to use
Hepatitis B immunoglobulin
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Restricted Drug Restricted
Red
Medical team to contact Clinical Virology at Central Manchester Foundation Trust (0161 276 8853) 
   
Rabies Immunoglobulin
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Restricted Drug Restricted
Red
Medical team to contact Clinical Virology at Central Manchester Foundation Trust (0161 276 8853) 
   
Tetanus immunoglobulin
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Formulary
Red

Treatment of clinical tetanus: IV tetanus immunoglobulin no longer available - use IV human normal immunoglobulin (eg: Octagam® 10%)


Prophylaxis of tetanus-prone wounds: There are intermittent supply problems with IM tetanus immunoglobulin - use Subgam® human normal immunoglobulin SC/IM


See Public Health England (PHE) Guidance for full details


 

 
Link  PHE: Recommendations on the treatment and prophylaxis of tetanus
   
Varicella-Zoster immunoglobulin
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Restricted Drug Restricted
Green 1
Medical team to contact Clinical Virology at Central Manchester Foundation Trust (0161 276 8853) 
   
14.05.03  Anti-D (Rho) immunoglobulin
Anti-D (Rh0) Immunoglobulin
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Formulary
Red
 
Link  NICE TA156: Anti-D in pregnant women
Link  PAT Guideline: Anti-D Prophylaxis in Pregnancy and Following Birth
   
 ....
 Non Formulary Items
Anthrax vaccine

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Non Formulary
 
Anti-D (Rh0) Immunoglobulin  (Rhophylac)

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Non Formulary
 
Anti-D (Rh0) Immunoglobulin  (WinRho SDF)

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Non Formulary
 
Hepatitis A vaccine Single Component  (Avaxim®)

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Non Formulary
 
Hepatitis A vaccine Single Component  (Epaxal®)

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Non Formulary
 
Hepatitis A vaccine Single Component  (Vaqta® Paediatric)

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Non Formulary
 
Human papilloma virus vaccine  (Cervarix)

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Non Formulary
 
Influenza vaccine  (Agrippal®)

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Non Formulary
 
Influenza vaccine  (Enzira®)

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Non Formulary
 
Influenza vaccine  (Fluarix®)

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Non Formulary
 
Influenza vaccine  (Imuvac®)

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Non Formulary
 
Influenza vaccine  (Influvac Sub Unit®)

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Non Formulary
 
Influenza Vaccine  (Intanza®)

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Non Formulary
 
Influenza Vaccines  (Pandemrix®)

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Non Formulary
 
Meningococcal A, C, W135, and Y conjugate vaccine  (Menveo)

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Non Formulary
 
Normal Immunoglobulin  (Aragam®)

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Non Formulary
 
Normal Immunoglobulin  (Flebogammadif®)

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Non Formulary
 
Normal immunoglobulin  (Gammanorm®)

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Non Formulary
 
Normal Immunoglobulin  (Gammaplex®)

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Non Formulary
 
Normal Immunoglobulin  (Gamunex®)

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Non Formulary
 
Normal Immunoglobulin  (Hizentra®)

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Non Formulary
 
Normal Immunoglobulin  (Kiovig®)

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Non Formulary
 
Pneumococcal polysaccharide conjugate vaccine (adsorbed)  (Synflorix®)

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Non Formulary
 
Polysaccharide Typhoid Vaccine  (Typherix)

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Non Formulary
 
Rabies vaccine  (Rabipur®)

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Non Formulary
 
Typhoid Live Oral vaccine  (Vivotif®)

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Non Formulary
 
Varicella Zoster vaccine  (Zostavax)

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Non Formulary
 
Varicella-zoster vaccine  (Varilrix)

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Non Formulary
 
  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Amber

Drugs designated amber are suitable for shared care arrangements under a shared care protocol. Prescribing may be transferred from secondary to primary care once the patient is stabilised and agreed shared care arrangements have been established. Alternatively primary care may initiate under the supervision of secondary care if this option is given in the shared care document. It is recommended that shared care arrangements should be drawn up following local discussion and agreement by prescribing parties.   

Black

These products have been reviewed by the GM Joint Formulary Group and have been deemed not suitable for prescribing for adults in primary or secondary care within Greater Manchester. These decisions have been made on the basis of safety, efficacy and cost-effectiveness of the products.  

Green

Not used   

Green 1

Drugs designated green1 are suitable for initiation and ongoing prescribing within primary care.   

Green 2

Drugs designated green2 can be initiated by primary care following written or verbal advice from a specialist and then be subsequently safely prescribed in primary care with little or no monitoring required.  

Green 3

Drugs designated green3 are suitable for on-going prescribing within primary care after specialist initiation and an initial review (unless specified) in secondary care. Little or no monitoring is required.  

Grey

Not suitable for routine prescribing but may be suitable for a defined patient population. Whilst prescribers should think very carefully before prescribing or recommending any of the products on the grey list, there may be exceptional instances when the use of one of these products is necessary for a particular patient.   

Red

Drugs designated red are considered to be specialist medicines and prescribing responsibility for these medicines should normally remain with the consultant or specialist clinician. These drugs should not be initiated or prescribed in primary care. It is recommended that the supply of these specialist medicines should be organised via the hospital pharmacy, this may include arranging for supply via a home care company.   

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