The Pennine Acute Hospitals
NHS Trust Formulary
 
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5 Infections
This chapter of the formulary is not an antibiotic prescribing guide and is not intended to guide treatment choice.

Please refer to the relevant Pennine Acute policies (e.g. the Antibiotic Policy for Adult Patients, or Antibiotic Guidelines for Paediatrics) when making treatment choices.
05-01-01-03 Broad-spectrum penicillins

Amoxicillin
Formulary
Capsules
Oral Suspension
Sachets
Injection

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Co-Amoxiclav
Formulary
Tablets
Oral Suspension
Injection

Restricted Item Co-amoxiclav is only recommended as first line treatment in specific indications. Refer to Antibiotic Policy.

The risk of acute liver toxicity is 6 times greater with co-amoxiclav than with amoxicillin. Cholestatic jaundice is more common in patients above the age of 65 and in males. The duration of treatment should not normally exceed 14 days.

Co-amoxiclav is a recognised cause of Clostridium difficile infections and its use should be restricted.

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Ampicillin
Non Formulary

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Co-Fluampicil
Non Formulary

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