02-05-05-02 Angiotensin-II receptor antagonists
Angiotensin-II receptor antagonists (ARBs) are more expensive that ACE inhibitors. Their use should be reserved only for patients who suffer from unacceptable side effects using ACE inhibitors. However, if patients have suffered angioedema with an ACE inhibitor then an ARB is NOT recommended.
In heart failure, it is important that ARBs are titrated up to their target dose (or maximum tolerated) as advised by NICE.